Manchester(MAN) to San Francisco(SFO) flight deals from £528*

Book our best prices between Manchester and San Francisco  within the next 6 months

£528
£1.9K
Displaying fares for December-2024
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Range£528-£1,924

Virgin Atlantic deals for flights from Manchester to San Francisco

Select travel class
Virgin Atlantic deals for flights from Manchester to San Francisco
From
To
Fare type
Dates
Price
FromManchester (MAN)ToSan Francisco (SFO)Round trip
/
Economy
17/09/2025 - 05/10/2025

Starting from

£533*

Seen: 20 hours ago

FromManchester (MAN)ToSan Francisco (SFO)Round trip
/
Economy
19/09/2025 - 05/10/2025

Starting from

£533*

Seen: 19 hours ago

FromManchester (MAN)ToSan Francisco (SFO)Round trip
/
Economy
27/09/2025 - 06/10/2025

Starting from

£535*

Seen: 16 hours ago

FromManchester (MAN)ToSan Francisco (SFO)Round trip
/
Economy
13/09/2025 - 29/09/2025

Starting from

£535*

Seen: 19 hours ago

FromManchester (MAN)ToSan Francisco (SFO)Round trip
/
Economy
31/10/2025 - 07/11/2025

Starting from

£534*

Seen: 1 day ago

FromManchester (MAN)ToSan Francisco (SFO)Round trip
/
Economy
27/08/2025 - 24/09/2025

Starting from

£538*

Seen: 39 minutes ago

Prices shown are per person. Cheapest fares may be hand baggage only. *Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional baggage fees and charges for optional products and services may apply.

From
To
Fare type
Dates
Price
FromManchester (MAN)ToSan Francisco (SFO)Round trip
/
Premium
23/09/2025 - 07/10/2025

Starting from

£1,119*

Seen: 3 hours ago

Prices shown are per person. *Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional baggage fees and charges for optional products and services may apply.

From
To
Fare type
Dates
Price
FromManchester (MAN)ToSan Francisco (SFO)Round trip
/
Upper Class
27/08/2025 - 24/09/2025

Starting from

£2,479*

Seen: 39 minutes ago

FromManchester (MAN)ToSan Francisco (SFO)Round trip
/
Upper Class
27/08/2025 - 24/09/2025

Starting from

£2,480*

Seen: 39 minutes ago

FromManchester (MAN)ToSan Francisco (SFO)Round trip
/
Upper Class
08/10/2025 - 22/10/2025

Starting from

£2,499*

Seen: 19 hours ago

FromManchester (MAN)ToSan Francisco (SFO)Round trip
/
Upper Class
08/10/2025 - 22/10/2025

Starting from

£2,501*

Seen: 19 hours ago

FromManchester (MAN)ToSan Francisco (SFO)Round trip
/
Upper Class
03/11/2025 - 10/11/2025

Starting from

£2,600*

Seen: 1 day ago

FromManchester (MAN)ToSan Francisco (SFO)Round trip
/
Upper Class
31/10/2025 - 07/11/2025

Starting from

£2,600*

Seen: 1 day ago

Prices shown are per person. *Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional baggage fees and charges for optional products and services may apply.

Flight deals from Manchester (MAN) to San Francisco (SFO)

Diamond status in APEX Health & Safety

Virgin Atlantic is incredibly proud to have been awarded Diamond status in Health and Safety by APEX and Simpliflying. This is the highest standard possible, and shows our unwavering commitment to keeping our staff and customers safe and sound throughout the Covid-19 pandemic. Initiatives like our complimentary Covid-19 insurance cover, our pre-flight testing, and our efforts to create the safest customer journey possible have helped us reached this fantastic achievement.