Manchester(MAN) to San Francisco(SFO) flight deals from £602*

Voucher or promo code

Book our best prices between Manchester and San Francisco  within the next 6 months

Flight tickets from Manchester to San Francisco on Virgin Atlantic

Prices shown are per person. Cheapest fares may be hand luggage only. *Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional baggage fees and charges for optional products and services may apply.

Explore flights using your Virgin Points

keyboard_arrow_down

Points fares shown are per person. Cheapest points fares may be hand baggage only. *Points fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional baggage fees and charges for optional products and services may apply.

From
To
Fare type
Dates
Price
Manchester (MAN)San Francisco (SFO)Round trip
/
Premium
29 Apr, 2026 - 13 May, 2026

Starting from

£1,196

Seen: 1 day ago

Prices shown are per person. Cheapest fares may be hand luggage only. *Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional baggage fees and charges for optional products and services may apply.

From
To
Fare type
Dates
Price
Manchester (MAN)San Francisco (SFO)Round trip
/
Upper Class
11 Aug, 2026 - 19 Aug, 2026

Starting from

£2,745

Seen: 1 day ago

Manchester (MAN)San Francisco (SFO)Round trip
/
Upper Class
11 Aug, 2026 - 19 Aug, 2026

Starting from

£2,749

Seen: 1 day ago

Manchester (MAN)San Francisco (SFO)Round trip
/
Upper Class
23 Jul, 2026 - 05 Aug, 2026

Starting from

£2,808

Seen: 1 day ago

Manchester (MAN)San Francisco (SFO)Round trip
/
Upper Class
11 Aug, 2026 - 19 Aug, 2026

Starting from

£2,973

Seen: 1 day ago

Manchester (MAN)San Francisco (SFO)Round trip
/
Upper Class
27 Apr, 2026 - 11 May, 2026

Starting from

£3,098

Seen: 3 hours ago

Manchester (MAN)San Francisco (SFO)Round trip
/
Upper Class
18 May, 2026 - 24 May, 2026

Starting from

£3,198

Seen: 15 hours ago

Prices shown are per person. *Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional baggage fees and charges for optional products and services may apply.

Flight deals from Manchester (MAN) to San Francisco (SFO)
Best overall airline in Europe 2025

Best overall airline in Europe 2025


Virgin Atlantic is incredibly proud to have been voted Europe's best airline once again in the APEX awards. Withholding status of Europe's best airline for 5 years running.