Manchester(MAN) to San Francisco(SFO) flight deals from £652*

Voucher or promo code

Book our best prices between Manchester and San Francisco  within the next 6 months

Mar 2026
From£922*
Seen: 1 day ago
Round trip/Economy
Apr 2026
From£682*
Seen: 1 day ago
Round trip/Economy
May 2026
From£731*
Seen: 1 day ago
Round trip/Economy
£781
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    • Range£781-£1,389

    Prices shown are per person. Cheapest fares may be hand baggage only. *Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional baggage fees and charges for optional products and services may apply.

    Flight tickets from Manchester to San Francisco on Virgin Atlantic

    • Manchester (MAN)to

      San Francisco (SFO)
      29 Sep, 2026 - 06 Oct, 2026
      Starting from
      £661
      Seen: 1 day ago
      Round trip
      Economy

      Manchester (MAN)to

      San Francisco (SFO)
      01 Sep, 2026 - 16 Sep, 2026
      Starting from
      £661
      Seen: 20 hours ago
      Round trip
      Economy

      Manchester (MAN)to

      San Francisco (SFO)
      08 Sep, 2026 - 07 Oct, 2026
      Starting from
      £661
      Seen: 23 hours ago
      Round trip
      Economy

      Manchester (MAN)to

      San Francisco (SFO)
      01 Sep, 2026 - 30 Sep, 2026
      Starting from
      £665
      Seen: 1 day ago
      Round trip
      Economy

    Prices shown are per person. Cheapest fares may be hand luggage only. *Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional baggage fees and charges for optional products and services may apply.

    Explore flights using your Virgin Points

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    • Manchester (MAN)to

      San Francisco (SFO)
      21 Sep, 2026 - 28 Sep, 2026
      Starting from
      43,000
      + £360
      Seen: 1 hour ago
      Round trip
      Economy

      Manchester (MAN)to

      San Francisco (SFO)
      24 Sep, 2026 - 01 Oct, 2026
      Starting from
      47,500
      + £373
      Seen: 1 hour ago
      Round trip
      Economy

    Points fares shown are per person. Cheapest points fares may be hand baggage only. *Points fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional baggage fees and charges for optional products and services may apply.

    From
    To
    Fare type
    Dates
    Price
    Manchester (MAN)San Francisco (SFO)Round trip
    /
    Premium    		10 Nov, 2026 - 17 Nov, 2026

    Starting from

    £1,239

    Seen: 1 day ago

    Manchester (MAN)San Francisco (SFO)Round trip
    /
    Premium    		09 Nov, 2026 - 16 Nov, 2026

    Starting from

    £1,239

    Seen: 1 day ago

    Manchester (MAN)San Francisco (SFO)Round trip
    /
    Premium    		10 Nov, 2026 - 17 Nov, 2026

    Starting from

    £1,240

    Seen: 1 day ago

    Manchester (MAN)San Francisco (SFO)Round trip
    /
    Premium    		09 Nov, 2026 - 16 Nov, 2026

    Starting from

    £1,244

    Seen: 1 day ago

    Manchester (MAN)San Francisco (SFO)Round trip
    /
    Premium    		09 Oct, 2026 - 13 Oct, 2026

    Starting from

    £1,278

    Seen: 1 day ago

    Prices shown are per person. Cheapest fares may be hand luggage only. *Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional baggage fees and charges for optional products and services may apply.

    From
    To
    Fare type
    Dates
    Price
    Manchester (MAN)San Francisco (SFO)Round trip
    /
    Upper Class    		22 Jan, 2027 - 05 Feb, 2027

    Starting from

    £3,011

    Seen: 19 hours ago

    Manchester (MAN)San Francisco (SFO)Round trip
    /
    Upper Class    		06 Dec, 2026 - 13 Dec, 2026

    Starting from

    £3,011

    Seen: 7 hours ago

    Manchester (MAN)San Francisco (SFO)Round trip
    /
    Upper Class    		06 Dec, 2026 - 13 Dec, 2026

    Starting from

    £3,015

    Seen: 7 hours ago

    Manchester (MAN)San Francisco (SFO)Round trip
    /
    Upper Class    		26 Dec, 2026 - 10 Jan, 2027

    Starting from

    £3,007

    Seen: 1 day ago

    Manchester (MAN)San Francisco (SFO)Round trip
    /
    Upper Class    		05 Dec, 2026 - 12 Dec, 2026

    Starting from

    £3,019

    Seen: 7 hours ago

    Manchester (MAN)San Francisco (SFO)Round trip
    /
    Upper Class    		26 Dec, 2026 - 10 Jan, 2027

    Starting from

    £3,011

    Seen: 1 day ago

    Prices shown are per person. *Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional baggage fees and charges for optional products and services may apply.

    Flight deals from Manchester (MAN) to San Francisco (SFO)
    Best overall airline in Europe 2025

    Best overall airline in Europe 2025


    Virgin Atlantic is incredibly proud to have been voted Europe's best airline once again in the APEX awards. Withholding status of Europe's best airline for 5 years running.