Manchester(MAN) to San Francisco(SFO) flight deals from £521*

Voucher or promo code

Book our best prices between Manchester and San Francisco  within the next 6 months

Jul 2025
From£794*
Seen: 10 hours ago
Round trip/Economy
£718
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    • Range£718-£1,212

    Prices shown are per person. Cheapest fares may be hand baggage only. *Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional baggage fees and charges for optional products and services may apply.

    Flight tickets from Manchester to San Francisco on Virgin Atlantic

    Prices shown are per person. Cheapest fares may be hand luggage only. *Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional baggage fees and charges for optional products and services may apply.

    Explore flights using your Virgin Points

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    Points fares shown are per person. Cheapest points fares may be hand baggage only. *Points fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional baggage fees and charges for optional products and services may apply.

    From
    To
    Fare type
    Dates
    Price
    Manchester (MAN)San Francisco (SFO)Round trip
    /
    Premium    		13 Apr, 2026 - 04 May, 2026

    Starting from

    £1,145

    Seen: 3 hours ago

    Prices shown are per person. Cheapest fares may be hand luggage only. *Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional baggage fees and charges for optional products and services may apply.

    From
    To
    Fare type
    Dates
    Price
    Manchester (MAN)San Francisco (SFO)Round trip
    /
    Upper Class    		05 May, 2026 - 19 May, 2026

    Starting from

    £2,536

    Seen: 1 day ago

    Manchester (MAN)San Francisco (SFO)Round trip
    /
    Upper Class    		13 Apr, 2026 - 04 May, 2026

    Starting from

    £2,628

    Seen: 3 hours ago

    Manchester (MAN)San Francisco (SFO)Round trip
    /
    Upper Class    		21 Mar, 2026 - 10 Apr, 2026

    Starting from

    £2,703

    Seen: 13 hours ago

    Manchester (MAN)San Francisco (SFO)Round trip
    /
    Upper Class    		01 May, 2026 - 15 May, 2026

    Starting from

    £2,736

    Seen: 1 day ago

    Manchester (MAN)San Francisco (SFO)Round trip
    /
    Upper Class    		01 May, 2026 - 15 May, 2026

    Starting from

    £2,739

    Seen: 1 day ago

    Manchester (MAN)San Francisco (SFO)Round trip
    /
    Upper Class    		23 May, 2026 - 06 Jun, 2026

    Starting from

    £2,781

    Seen: 1 hour ago

    Prices shown are per person. *Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional baggage fees and charges for optional products and services may apply.

    Flight deals from Manchester (MAN) to San Francisco (SFO)
    Best overall airline in Europe 2025

    Best overall airline in Europe 2025


    Virgin Atlantic is incredibly proud to have been voted Europe's best airline once again in the APEX awards. Withholding status of Europe's best airline for 5 years running.