Manchester(MAN) to San Francisco(SFO) flight deals from £546*
Book our best prices between Manchester and San Francisco within the next 6 months
Flight tickets from Manchester to San Francisco on Virgin Atlantic
Prices shown are per person. Cheapest fares may be hand luggage only. *Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional baggage fees and charges for optional products and services may apply.
Explore flights using your Virgin Points
Points fares shown are per person. Cheapest points fares may be hand baggage only. *Points fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional baggage fees and charges for optional products and services may apply.
From | To | Fare type | Dates | Price |
|---|---|---|---|---|
| Manchester (MAN) | San Francisco (SFO) | Round trip / Premium | 05 Oct, 2026 - 20 Oct, 2026 | Starting from £1,165 Seen: 17 hours ago |
Prices shown are per person. Cheapest fares may be hand luggage only. *Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional baggage fees and charges for optional products and services may apply.
From | To | Fare type | Dates | Price |
|---|---|---|---|---|
| Manchester (MAN) | San Francisco (SFO) | Round trip / Upper Class | 19 Aug, 2026 - 23 Sep, 2026 | Starting from £2,519 Seen: 1 day ago |
| Manchester (MAN) | San Francisco (SFO) | Round trip / Upper Class | 01 Jul, 2026 - 09 Jul, 2026 | Starting from £2,538 Seen: 1 day ago |
| Manchester (MAN) | San Francisco (SFO) | Round trip / Upper Class | 03 Sep, 2026 - 23 Sep, 2026 | Starting from £2,548 Seen: 1 day ago |
| Manchester (MAN) | San Francisco (SFO) | Round trip / Upper Class | 26 Jun, 2026 - 30 Jun, 2026 | Starting from £2,551 Seen: 5 hours ago |
| Manchester (MAN) | San Francisco (SFO) | Round trip / Upper Class | 26 Jun, 2026 - 30 Jun, 2026 | Starting from £2,554 Seen: 5 hours ago |
| Manchester (MAN) | San Francisco (SFO) | Round trip / Upper Class | 20 Aug, 2026 - 03 Sep, 2026 | Starting from £2,602 Seen: 1 day ago |
Prices shown are per person. *Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional baggage fees and charges for optional products and services may apply.
Alternative Routes from Manchester or to San Francisco
 |
Best overall airline in Europe 2025Virgin Atlantic is incredibly proud to have been voted Europe's best airline once again in the APEX awards. Withholding status of Europe's best airline for 5 years running. |
Explore Virgin Atlantic's Top-Pick Destinations