Manchester(MAN) to San Francisco(SFO) flight deals from £646*

Voucher or promo code

Book our best prices between Manchester and San Francisco  within the next 6 months

Jun 2026
From£836*
Seen: 1 day ago
Round trip/Economy
Jul 2026
From£688*
Seen: 1 day ago
Round trip/Economy
Aug 2026
From£683*
Seen: 13 hours ago
Round trip/Economy
cmp-daily-histogram-bars-legend-min-price-aria-label £688
cmp-daily-histogram-bars-legend-max-price-aria-label £1.2K
Displaying fares for June-2026
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    • Range£688-£1,183

    Prices shown are per person. Cheapest fares may be hand baggage only. *Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional baggage fees and charges for optional products and services may apply.

    Flight tickets from Manchester to San Francisco on Virgin Atlantic

    • Manchester (MAN)to

      San Francisco (SFO)
      14 Dec, 2026 - 06 Jan, 2027
      Starting from
      £674
      Seen: 1 day ago
      Round trip
      Economy

      Manchester (MAN)to

      San Francisco (SFO)
      20 Nov, 2026 - 25 Nov, 2026
      Starting from
      £674
      Seen: 1 day ago
      Round trip
      Economy

      Manchester (MAN)to

      San Francisco (SFO)
      24 Nov, 2026 - 03 Dec, 2026
      Starting from
      £674
      Seen: 9 hours ago
      Round trip
      Economy

      Manchester (MAN)to

      San Francisco (SFO)
      24 Mar, 2027 - 14 Apr, 2027
      Starting from
      £674
      Seen: 9 hours ago
      Round trip
      Economy

    Prices shown are per person. Cheapest fares may be hand luggage only. *Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional baggage fees and charges for optional products and services may apply.

    Explore flights using your Virgin Points

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    • Manchester (MAN)to

      San Francisco (SFO)
      14 Feb, 2027 - 21 Feb, 2027
      Starting from
      30,000
      + £443
      Seen: 1 day ago
      Round trip
      Economy

      Manchester (MAN)to

      San Francisco (SFO)
      11 Feb, 2027 - 18 Feb, 2027
      Starting from
      30,000
      + £443
      Seen: 1 day ago
      Round trip
      Economy

    Points fares shown are per person. Cheapest points fares may be hand baggage only. *Points fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional baggage fees and charges for optional products and services may apply.

    From
    To
    Fare type
    Dates
    Price
    Manchester (MAN)San Francisco (SFO)Round trip
    /
    Premium    		17 Apr, 2027 - 24 Apr, 2027

    Starting from

    £1,389

    Seen: 5 hours ago

    Manchester (MAN)San Francisco (SFO)Round trip
    /
    Premium    		17 Apr, 2027 - 24 Apr, 2027

    Starting from

    £1,390

    Seen: 5 hours ago

    Manchester (MAN)San Francisco (SFO)Round trip
    /
    Premium    		28 Apr, 2027 - 12 May, 2027

    Starting from

    £1,389

    Seen: 13 hours ago

    Manchester (MAN)San Francisco (SFO)Round trip
    /
    Premium    		11 Feb, 2027 - 18 Feb, 2027

    Starting from

    £1,381

    Seen: 1 day ago

    Manchester (MAN)San Francisco (SFO)Round trip
    /
    Premium    		11 Feb, 2027 - 18 Feb, 2027

    Starting from

    £1,382

    Seen: 1 day ago

    Prices shown are per person. Cheapest fares may be hand luggage only. *Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional baggage fees and charges for optional products and services may apply.

    From
    To
    Fare type
    Dates
    Price
    Manchester (MAN)San Francisco (SFO)Round trip
    /
    Upper Class    		24 Mar, 2027 - 14 Apr, 2027

    Starting from

    £3,208

    Seen: 9 hours ago

    Manchester (MAN)San Francisco (SFO)Round trip
    /
    Upper Class    		24 Mar, 2027 - 14 Apr, 2027

    Starting from

    £3,212

    Seen: 9 hours ago

    Manchester (MAN)San Francisco (SFO)Round trip
    /
    Upper Class    		17 Apr, 2027 - 24 Apr, 2027

    Starting from

    £3,270

    Seen: 5 hours ago

    Manchester (MAN)San Francisco (SFO)Round trip
    /
    Upper Class    		29 Mar, 2027 - 05 Apr, 2027

    Starting from

    £3,208

    Seen: 1 day ago

    Manchester (MAN)San Francisco (SFO)Round trip
    /
    Upper Class    		30 Mar, 2027 - 27 Apr, 2027

    Starting from

    £3,258

    Seen: 18 hours ago

    Manchester (MAN)San Francisco (SFO)Round trip
    /
    Upper Class    		30 Mar, 2027 - 28 Apr, 2027

    Starting from

    £3,258

    Seen: 18 hours ago

    Prices shown are per person. *Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional baggage fees and charges for optional products and services may apply.

    Flight deals from Manchester (MAN) to San Francisco (SFO)
    Best overall airline in Europe 2025

    Best overall airline in Europe 2025


    Virgin Atlantic is incredibly proud to have been voted Europe's best airline once again in the APEX awards. Withholding status of Europe's best airline for 5 years running.