Manchester(MAN) to Saint Louis(STL) flight deals from £672*

Voucher or promo code

Book our best prices between Manchester and Saint Louis  within the next 6 months

Prices shown are per person. Cheapest fares may be hand baggage only. *Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional baggage fees and charges for optional products and services may apply.

Flight tickets from Manchester to Saint Louis on Virgin Atlantic

  • Manchester (MAN)to

    Saint Louis (STL)
    10 Sep, 2026 - 02 Oct, 2026
    Starting from
    £742
    Seen: 1 day ago
    Round trip
    Economy

    Manchester (MAN)to

    Saint Louis (STL)
    10 Sep, 2026 - 02 Oct, 2026
    Starting from
    £742
    Seen: 1 day ago
    Round trip
    Economy

    Manchester (MAN)to

    Saint Louis (STL)
    22 Oct, 2026 - 05 Nov, 2026
    Starting from
    £754
    Seen: 11 hours ago
    Round trip
    Economy

    Manchester (MAN)to

    Saint Louis (STL)
    22 Oct, 2026 - 05 Nov, 2026
    Starting from
    £754
    Seen: 11 hours ago
    Round trip
    Economy

Prices shown are per person. Cheapest fares may be hand luggage only. *Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional baggage fees and charges for optional products and services may apply.

Explore flights using your Virgin Points

keyboard_arrow_down

Points fares shown are per person. Cheapest points fares may be hand baggage only. *Points fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional baggage fees and charges for optional products and services may apply.

From
To
Fare type
Dates
Price
Manchester (MAN)Saint Louis (STL)Round trip
/
Premium		08 Sep, 2026 - 30 Sep, 2026

Starting from

£1,555

Seen: 1 day ago

Manchester (MAN)Saint Louis (STL)Round trip
/
Premium		08 Sep, 2026 - 30 Sep, 2026

Starting from

£1,560

Seen: 1 day ago

Manchester (MAN)Saint Louis (STL)Round trip
/
Premium		08 Sep, 2026 - 30 Sep, 2026

Starting from

£1,585

Seen: 1 day ago

Manchester (MAN)Saint Louis (STL)Round trip
/
Premium		09 Sep, 2026 - 01 Oct, 2026

Starting from

£1,585

Seen: 1 day ago

Manchester (MAN)Saint Louis (STL)Round trip
/
Premium		10 Sep, 2026 - 02 Oct, 2026

Starting from

£1,615

Seen: 1 day ago

Prices shown are per person. Cheapest fares may be hand luggage only. *Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional baggage fees and charges for optional products and services may apply.

From
To
Fare type
Dates
Price
Manchester (MAN)Saint Louis (STL)Round trip
/
Upper Class		23 Oct, 2026 - 06 Nov, 2026

Starting from

£2,888

Seen: 11 hours ago

Manchester (MAN)Saint Louis (STL)Round trip
/
Upper Class		23 Oct, 2026 - 06 Nov, 2026

Starting from

£3,128

Seen: 11 hours ago

Manchester (MAN)Saint Louis (STL)Round trip
/
Upper Class		08 Sep, 2026 - 30 Sep, 2026

Starting from

£3,163

Seen: 1 day ago

Manchester (MAN)Saint Louis (STL)Round trip
/
Upper Class		10 Sep, 2026 - 02 Oct, 2026

Starting from

£3,263

Seen: 1 day ago

Manchester (MAN)Saint Louis (STL)Round trip
/
Upper Class		09 Sep, 2026 - 01 Oct, 2026

Starting from

£3,263

Seen: 1 day ago

Manchester (MAN)Saint Louis (STL)Round trip
/
Upper Class		08 Sep, 2026 - 30 Sep, 2026

Starting from

£3,403

Seen: 1 day ago

Prices shown are per person. *Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional baggage fees and charges for optional products and services may apply.

Flight deals from Manchester (MAN) to Saint Louis (STL)
Best overall airline in Europe 2025

Best overall airline in Europe 2025


Virgin Atlantic is incredibly proud to have been voted Europe's best airline once again in the APEX awards. Withholding status of Europe's best airline for 5 years running.