Manchester(MAN) to Knoxville(TYS) flight deals from £779*

Voucher or promo code

Book our best prices between Manchester and Knoxville  within the next 6 months

Prices shown are per person. Cheapest fares may be hand baggage only. *Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional baggage fees and charges for optional products and services may apply.

Flight tickets from Manchester to Knoxville on Virgin Atlantic

  • Manchester (MAN)to

    Knoxville (TYS)
    30 Oct, 2026 - 06 Nov, 2026
    Starting from
    £795
    Seen: 6 hours ago
    Round trip
    Economy

    Manchester (MAN)to

    Knoxville (TYS)
    09 Mar, 2026 - 07 Apr, 2026
    Starting from
    £802
    Seen: 15 hours ago
    Round trip
    Economy

    Manchester (MAN)to

    Knoxville (TYS)
    31 Oct, 2026 - 07 Nov, 2026
    Starting from
    £803
    Seen: 6 hours ago
    Round trip
    Economy

    Manchester (MAN)to

    Knoxville (TYS)
    01 Jun, 2026 - 08 Jun, 2026
    Starting from
    £848
    Seen: 6 hours ago
    Round trip
    Economy

Prices shown are per person. Cheapest fares may be hand luggage only. *Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional baggage fees and charges for optional products and services may apply.

Explore flights using your Virgin Points

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Points fares shown are per person. Cheapest points fares may be hand baggage only. *Points fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional baggage fees and charges for optional products and services may apply.

From
To
Fare type
Dates
Price
Manchester (MAN)Knoxville (TYS)Round trip
/
Premium		07 Jan, 2027 - 15 Jan, 2027

Starting from

£1,512

Seen: 9 hours ago

Manchester (MAN)Knoxville (TYS)Round trip
/
Premium		07 Jan, 2027 - 15 Jan, 2027

Starting from

£1,512

Seen: 9 hours ago

Manchester (MAN)Knoxville (TYS)Round trip
/
Premium		31 Oct, 2026 - 07 Nov, 2026

Starting from

£1,521

Seen: 6 hours ago

Manchester (MAN)Knoxville (TYS)Round trip
/
Premium		20 Dec, 2026 - 29 Dec, 2027

Starting from

£1,603

Seen: 1 day ago

Manchester (MAN)Knoxville (TYS)Round trip
/
Premium		10 Oct, 2026 - 19 Oct, 2026

Starting from

£1,631

Seen: 1 day ago

Prices shown are per person. Cheapest fares may be hand luggage only. *Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional baggage fees and charges for optional products and services may apply.

From
To
Fare type
Dates
Price
Manchester (MAN)Knoxville (TYS)Round trip
/
Upper Class		07 Jan, 2027 - 15 Jan, 2027

Starting from

£2,554

Seen: 9 hours ago

Manchester (MAN)Knoxville (TYS)Round trip
/
Upper Class		07 Jan, 2027 - 15 Jan, 2027

Starting from

£2,784

Seen: 9 hours ago

Manchester (MAN)Knoxville (TYS)Round trip
/
Upper Class		07 Jan, 2027 - 15 Jan, 2027

Starting from

£2,794

Seen: 9 hours ago

Manchester (MAN)Knoxville (TYS)Round trip
/
Upper Class		19 Dec, 2026 - 28 Dec, 2027

Starting from

£2,779

Seen: 1 day ago

Manchester (MAN)Knoxville (TYS)Round trip
/
Upper Class		10 Oct, 2026 - 19 Oct, 2026

Starting from

£2,838

Seen: 1 day ago

Manchester (MAN)Knoxville (TYS)Round trip
/
Upper Class		20 Dec, 2026 - 29 Dec, 2027

Starting from

£3,004

Seen: 1 day ago

Prices shown are per person. *Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional baggage fees and charges for optional products and services may apply.

Flight deals from Manchester (MAN) to Knoxville (TYS)
Best overall airline in Europe 2025

Best overall airline in Europe 2025


Virgin Atlantic is incredibly proud to have been voted Europe's best airline once again in the APEX awards. Withholding status of Europe's best airline for 5 years running.