Manchester(MAN) to San Francisco(SFO) flight deals from £521*

Voucher or promo code

Book our best prices between Manchester and San Francisco  within the next 6 months

£718
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  • Range£718-£1,212

    Flight tickets from Manchester to San Francisco on Virgin Atlantic

    £

    Prices shown are per person. Cheapest fares may be hand luggage only. *Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional baggage fees and charges for optional products and services may apply.

    Explore flights using your Virgin Points

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    Points fares shown are per person. Cheapest points fares may be hand baggage only. *Points fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional baggage fees and charges for optional products and services may apply.

    Find Premium flight deals

    Skip the queues and experience an extra large leather seat with a seat pitch of up to 38 inches and extra legroom. You also get 10kg hand luggage and 2 x 23kg checked bags and you are welcomed on board with a glass of bubbly. There is a choice of 3 main courses and it is all served on china. It's the little extras that make a huge difference.

    £
    From
    To
    Fare type
    Dates
    Price
    Manchester (MAN)San Francisco (SFO)Round trip
    /
    Premium
    13 Apr, 2026 - 04 May, 2026

    Starting from

    £1,145

    Seen: 4 hours ago

    Prices shown are per person. Cheapest fares may be hand luggage only. *Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional baggage fees and charges for optional products and services may apply.

    Find Upper Class flight deals


    Enjoy creature comforts in your own personal space, with loads of leg room, oodles of entertainment and drinks delivered on demand. And when it's time to hit the sack, your seat transforms into a fully flat bed, designed to give to you a fresh start in the morning. You also get 2 pieces of 16kg hand luggage and 2 x 32kg checked bags plus you are welcomed on board with a glass of bubbly. There is a choice of tasty 4 course meals and you can even get breakfast in bed. Experience the next level of luxurious travel.

    Man on board in Premium cabin

    £
    From
    To
    Fare type
    Dates
    Price
    Manchester (MAN)San Francisco (SFO)Round trip
    /
    Upper Class
    05 May, 2026 - 19 May, 2026

    Starting from

    £2,536

    Seen: 1 day ago

    Manchester (MAN)San Francisco (SFO)Round trip
    /
    Upper Class
    13 Apr, 2026 - 04 May, 2026

    Starting from

    £2,628

    Seen: 4 hours ago

    Manchester (MAN)San Francisco (SFO)Round trip
    /
    Upper Class
    21 Mar, 2026 - 10 Apr, 2026

    Starting from

    £2,703

    Seen: 14 hours ago

    Manchester (MAN)San Francisco (SFO)Round trip
    /
    Upper Class
    01 May, 2026 - 15 May, 2026

    Starting from

    £2,736

    Seen: 1 day ago

    Manchester (MAN)San Francisco (SFO)Round trip
    /
    Upper Class
    01 May, 2026 - 15 May, 2026

    Starting from

    £2,739

    Seen: 1 day ago

    Manchester (MAN)San Francisco (SFO)Round trip
    /
    Upper Class
    23 May, 2026 - 06 Jun, 2026

    Starting from

    £2,781

    Seen: 2 hours ago

    Prices shown are per person. *Fares displayed have been collected within the last 48hrs and may no longer be available at time of booking. Additional baggage fees and charges for optional products and services may apply.

    Flight deals from Manchester (MAN) to San Francisco (SFO)
    Best overall airline in Europe 2025

    Best overall airline in Europe 2025


    Virgin Atlantic is incredibly proud to have been voted Europe's best airline once again in the APEX awards. Withholding status of Europe's best airline for 5 years running.